LimsPulse
Titration & electrochemistry

Potentiometric Titrator (Autotitrator)

Adds a titrant from a motorised burette while an electrode measures the potential of the solution, and finds the equivalence point from the change in potential. Used for assays, standardisation and many limit tests.

  • Pharmaceutical
  • Chemicals
  • Food & beverage
  • Environmental
  • Metal finishing
Photo of a Potentiometric Titrator (Autotitrator)
Photo: User:FA2010, Public domain (cropped), via Wikimedia Commons
CALIBRATION

Potentiometric titrator calibration procedures

QUALIFICATION

Instrument qualification (DQ · IQ · OQ · PQ)

  1. 01

    DQ — Design qualification

    Lists the needs, such as number of burettes, burette sizes, electrode types, sample changer and compliant software, and confirms the selected system meets them.

  2. 02

    IQ — Installation qualification

    Records components, serial numbers, firmware and software versions, and correct installation in the intended location.

  3. 03

    OQ — Operational qualification

    Tests burette volume accuracy and precision, mV measurement accuracy with a calibrated simulator, temperature measurement and stirrer function.

  4. 04

    PQ — Performance qualification

    Titrates a certified standard, for example potassium hydrogen phthalate, and confirms recovery and repeatability within limits over time.

In LimsPulse · Calibration Management

Keep every Potentiometric titrator in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.

See how