Lab glossary
High molecular weight species (HMW)
Forms of a protein larger than the monomer, mainly dimers and larger aggregates. In SEC-HPLC they elute before the monomer and are reported as area %.
- Also: HMW
- Also: HMWS
- Also: aggregates
- Also: dimer
Where you will meet this term
- InstrumentGel Permeation / Size-Exclusion Chromatography (GPC / SEC)
- InstrumentAggregate Impact Value Tester
- Test methodSieve Analysis of Aggregates (Grading and Fineness Modulus)
- Test methodAggregate Impact Value (AIV)
- Test methodSpecific Gravity and Water Absorption of Coarse Aggregate
- Test methodProtein Concentration by UV Absorbance at 280 nm (A280)
- Test methodPurity by SDS-PAGE (reduced and non-reduced)
- Test methodAggregates by size-exclusion HPLC (SEC-HPLC)