Karl Fischer Titrator (Volumetric)
Measures the water content of a sample by titrating it with an iodine-containing Karl Fischer reagent from a motorised burette. The standard method for water in APIs, excipients and many finished products.
- Pharmaceutical
- Chemicals
- Food & beverage
- Petrochemicals
- Cosmetics
KF titrator (volumetric) calibration procedures
Titre determination
Determines how many mg of water 1 mL of KF reagent reacts with, using a water standard such as sodium tartrate dihydrate.
Open procedureBurette accuracy
Checks that the motorised burette delivers the volume it reports, by weighing dispensed water and converting mass to volume.
Open procedureDrift check
Confirms the conditioned titration cell is tight, by checking that the background drift is low and stable before use.
Open procedureInstrument qualification (DQ · IQ · OQ · PQ)
- 01
DQ — Design qualification
Documents the user requirements, such as volumetric range, burette sizes, drift measurement, oven option and software with audit trail, and confirms the chosen model meets them.
- 02
IQ — Installation qualification
Confirms correct delivery and installation: titrator, burette units, cell, electrode, serial numbers, software version and manuals.
- 03
OQ — Operational qualification
Checks burette accuracy gravimetrically, electrode function and drift, and recovery with a certified water standard.
- 04
PQ — Performance qualification
Shows routine performance over time, for example regular titre determinations and recovery checks with a water standard within limits.
Keep every KF titrator (volumetric) in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.