Lab glossary
Low molecular weight species (LMW)
Forms of a protein smaller than the intact molecule, such as fragments from cleavage of the peptide chain. In SEC-HPLC they elute after the monomer.
- Also: LMW
- Also: LMWS
- Also: fragments
- Also: clips
Where you will meet this term
- InstrumentDisintegration Test Apparatus
- InstrumentGas Chromatography–Mass Spectrometry (GC-MS)
- InstrumentGel electrophoresis system
- Test methodDisintegration Time of Tablets and Capsules
- Test methodPurity by SDS-PAGE (reduced and non-reduced)
- Test methodAggregates by size-exclusion HPLC (SEC-HPLC)
- Test methodResidual host cell DNA by quantitative PCR (qPCR)