LimsPulse
Bioanalytical

Capillary electrophoresis system

Separates charged molecules in a thin fused-silica capillary under a high voltage (typically up to 30 kV). Used in biologics QC for size purity (CE-SDS), charge variants (cIEF, CZE) and glycan analysis.

  • Biotechnology
  • Biopharmaceutical
  • Pharmaceutical
  • Genomics
  • Forensic science
  • Academic research
Photo of a Capillary electrophoresis system
Photo: Mark Pellegrini, CC BY-SA 3.0 (cropped), via Wikimedia Commons
PREVENTIVE MAINTENANCE

Maintenance checklist

Each sequence

  • Check electrodes and interface block for salt deposits; clean if needed
  • Record capillary injection count

Weekly

  • Clean electrodes and the interface block
  • Check cooling liquid level (if liquid-cooled)

Every 6–12 months

  • Verify capillary temperature, high voltage and current with calibrated tools
  • Verify detector wavelength accuracy and noise
  • Check injection precision with a test mix

As needed

  • Replace capillary when performance falls
  • Replace detector lamp
  • Preventive maintenance by the supplier
SAFETY

Safety precautions

Before you work on the CE
  • CE systems use up to about 30 kV. Never defeat safety interlocks.
  • SDS, reducing and alkylating agents (such as iodoacetamide) are irritant or toxic. Wear gloves and eye protection.
  • UV lamps can harm eyes; keep covers closed.
  • Sodium hydroxide and acids used for capillary conditioning are corrosive.
In LimsPulse · Calibration Management

Keep every CE in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.

See how