Chromatography
Ion Chromatograph (IC)
Separates charged species (anions, cations, small organic acids and amines) on an ion-exchange column and usually detects them by conductivity. Used in pharma QC for counter-ions, inorganic impurities and ions in water.
- Pharmaceutical
- Power and water utilities
- Environmental
- Food & beverage
- Semiconductor
- Chemicals
PREVENTIVE MAINTENANCE
Maintenance checklist
Daily / each use
- Record background conductivity and pressure
- Check eluent level or generator cartridge status
- Check for leaks and salt deposits at fittings
Weekly
- Replace eluent and rinse the reservoir
- Check the autosampler and waste lines
Monthly / quarterly
- Replace pump inlet filters
- Check guard column performance and replace if peak shape degrades
- Clean the suppressor if background rises
Six-monthly / annual
- Preventive maintenance (pump seals, check valves)
- Calibration of flow rate and conductivity detector
SAFETY
Safety precautions
Before you work on the IC
- Hydroxide and acid eluents are corrosive: wear gloves and eye protection.
- Eluent generators and electrolytic suppressors produce small amounts of hydrogen and oxygen gas; keep vents clear.
- Never loosen fittings while the system is under pressure.
- Dispose of eluent and sample waste as per site procedure.
In LimsPulse · Calibration Management
Keep every IC in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.