LimsPulse
Bioanalytical

Automated cell counter

Counts cells and measures their viability automatically, usually by imaging a stained sample in a disposable or reusable counting chamber. It replaces manual haemocytometer counting for routine cell culture and bioprocess work.

  • Biotechnology
  • Biopharmaceutical
  • Cell and gene therapy
  • Academic research
  • Vaccine manufacture
  • Regenerative medicine
Photo of a Automated cell counter
Photo: TimVickers, Public domain (cropped), via Wikimedia Commons
PREVENTIVE MAINTENANCE

Maintenance checklist

Daily / each use

  • Keep the slide port clean and dry
  • Check the self-test or focus check passes

Weekly

  • Clean the optics window as the manual describes
  • Check stain stock for crystals or contamination

Monthly or as per SOP

  • Count certified reference beads to verify accuracy and precision
  • Compare with a manual haemocytometer count for key cell types

Annual

  • Preventive maintenance and full bead verification by the supplier
  • Review software version and protocol settings
SAFETY

Safety precautions

Before you work on the Cell counter
  • Cell samples may be biohazardous. Follow your site biosafety rules and use a biosafety cabinet where required.
  • Trypan blue is classed as a possible carcinogen. Wear gloves and avoid skin contact.
  • Fluorescent nucleic acid stains (AO, PI) are mutagenic. Handle and dispose of them as hazardous chemicals.
In LimsPulse · Calibration Management

Keep every Cell counter in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.

See how