Dosage-form testing
Tablet Friability Tester (Friabilator)
Tumbles a sample of uncoated tablets in a rotating drum to see how much weight they lose by chipping and abrasion. Shows whether tablets can survive coating, packing and transport.
- Pharmaceutical
- Nutraceuticals
- Veterinary medicines
- Food tablets
TROUBLESHOOTING
Common problems, causes and fixes
Weight gain after the test
Likely causes
- • Tablets absorbed moisture
- • Uneven dedusting
What to do
- • Test in controlled humidity and weigh promptly
- • Dedust consistently
Tablets do not tumble (slide or jam)
Likely causes
- • Large or unusual tablet shape
- • Damaged drum projection
What to do
- • Use the tilted-drum set-up permitted by the chapter
- • Replace the drum
Revolution count or time wrong
Likely causes
- • Motor speed drift
- • Counter fault
What to do
- • Verify speed with a stopwatch or tachometer and service the drive
High friability on a batch that is usually fine
Likely causes
- • Low hardness from the press
- • Capping or lamination
What to do
- • Check in-process hardness and press settings
- • Inform production and investigate
In LimsPulse · Calibration Management
Keep every Friability tester in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.