LimsPulse
Dosage-form testing

Tablet Friability Tester (Friabilator)

Tumbles a sample of uncoated tablets in a rotating drum to see how much weight they lose by chipping and abrasion. Shows whether tablets can survive coating, packing and transport.

  • Pharmaceutical
  • Nutraceuticals
  • Veterinary medicines
  • Food tablets
Illustration of Tablet Friability Tester (Friabilator)
Follow your site SOP
This is a typical operating sequence for learning. Your instrument model and approved SOP take precedence.
STAGE 1

Before you start

  1. 1Check the calibration status label.
  2. 2Clean the drum so it is free of dust and fragments.
  3. 3Check the analytical balance used for weighing is calibrated and level.
  • Use a balance with adequate readability (commonly 1 mg or better for a 6.5 g sample).
STAGE 2

Testing

  1. 1Take the sample size stated in your procedure and remove loose dust with a soft brush or air.
  2. 2Weigh the tablets accurately and record W1.
  3. 3Put the tablets in the drum, close the lid and set 100 revolutions.
  4. 4Start the drum and let it complete the revolutions.
  5. 5Remove the tablets, dedust them in the same way and weigh again (W2).
  6. 6Inspect for cracked, capped or broken tablets.
  • Dedust the same way before and after; uneven dedusting gives a false weight loss or gain.
STAGE 3

After testing

  1. 1Clean the drum
  2. 2Complete the usage log
In LimsPulse · Calibration Management

Keep every Friability tester in control: usage logs, calibration and maintenance schedules, and automatic blocking of overdue instruments.

See how