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Lab glossary

Charge variants

Forms of a protein that differ in net charge, for example from deamidation or sialylation (acidic) or C-terminal lysine (basic). Separated by cIEF or cation-exchange chromatography and reported as acidic, main and basic %.

  • Also: charge heterogeneity
  • Also: acidic variants
  • Also: basic variants

Where you will meet this term